Fucoidan helps to regenerate skin cells and activates the natural restorative ability of the skin by promoting the production of the heparin-binding polypeptide hepatocellular growth factor (HGF) within human organisms. HGF's effects also include restoring damaged liver tissue and repairing blood vessels. Fucoidan is also used for protecting skin moisture and several experiments show that fucoidan has moisturizing effects exceeding those of HA. It helps whiten the skin, too. Fucoidan is known to protect skin from UV radiation and inhibit the production of melanin in skin that has already been exposed to the sun's rays. It creates an antiinflammation protection barrier. Fucoidan has been proven to have an antiinflammatory effect on skin…

Science Direct

Fucoidan, one kind of DS, has been reported to exhibit anti-inflammatory, antibacterial, antiviral, immunomodulating, antiangiogenesis, and antitumor activities. Fucoidan, a sulfated polysaccharide found in the cell walls of various species of brown and green seaweeds, is known to contain large proportions of L-fucose and sulfate along with low amounts of xylose, uronic acid, and galactose. Seaweed and marine algae have been used as a food and medicine for over a thousand years in Asia and in some parts of northern Europe. Recently, the antitumor effect of fucoidan has been studied intensively. Studies have reported that the intake of seaweed is associated with a lower incidence of breast cancer. A recent study of patients with unresectable advanced or recurrent colorectal cancer suggests that fucoidan has the potential to reduce the toxicities of chemotherapy…

Harvard

Treatment of fucoidan resulted in potent and persistent reduction of high blood pressure (BP) even after drug withdrawal. Our results showed that the mechanisms might involve protection against vascular structure damage, enhanced endothelium-independent vascular function and inhibition of abnormal proliferation of smooth muscle cells, which are mediated by the Akt–eNOS signaling pathway. Moreover, fucoidan treatment reduced the vascular inflammation and oxidative stress control caused by iNOS expression. Together, these results support a putative role of fucoidan in hypertension prevention and treatment.

Royal Society of Chemistry

The chemical composition of fucoidan, a kind of sulfated polysaccharide mainly derived from brown seaweed, includes a substantial percentage of l-fucose. Fucoidan has various biological and pharmacological activities, such as anti-cancer/anti-tumor, anti-proliferation, anti-inflammatory and immune-modulatory functions, and fucoidan-related dietary supplements and nutraceuticals have recently drawn considerable attention.

NIH National Center of Biotechnology Information